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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEK4 All Species: 5.76
Human Site: S570 Identified Species: 11.52
UniProt: P51957 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51957 NP_003148.2 841 94597 S570 S P P R F L P S H P I V G K V
Chimpanzee Pan troglodytes XP_516519 889 99702 S644 Q R R V V T G S V S S S R S S
Rhesus Macaque Macaca mulatta XP_001082793 1258 142958 S881 S P E C T E A S P Q M S L K L
Dog Lupus familis XP_533795 879 98359 S609 A P P R L L P S L P T A G K K
Cat Felis silvestris
Mouse Mus musculus Q9Z1J2 792 88976 T546 G C V N S S R T S S T A S A K
Rat Rattus norvegicus NP_001013152 793 89178 S548 R S V N G S R S S S T A S S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521008 756 85471 N512 T E A T G S G N K E V A S S K
Chicken Gallus gallus XP_414252 807 90823 N545 L P F P T D V N V K T A Q S C
Frog Xenopus laevis Q7ZZC8 944 104521 G657 D N H I F A W G N G G N G R L
Zebra Danio Brachydanio rerio Q90XC2 697 76523 V453 A L L G Y E L V Q V S C G A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SLI2 612 68818 K368 V S K Y P L A K S S V T S R R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48479 858 94329 Q599 S G V S S I G Q H P L R S A P
Conservation
Percent
Protein Identity: 100 88.4 25.5 73 N.A. 72.2 72.4 N.A. 57 58.8 21 25.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 88.6 42.5 80.1 N.A. 80.5 79.7 N.A. 68 71.6 37.7 43.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 26.6 60 N.A. 0 6.6 N.A. 0 6.6 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 40 66.6 N.A. 6.6 6.6 N.A. 20 13.3 33.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.6 N.A. 20.9
Protein Similarity: N.A. N.A. N.A. 44.3 N.A. 39.2
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. 20
P-Site Similarity: N.A. N.A. N.A. 20 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 9 0 0 9 17 0 0 0 0 42 0 25 0 % A
% Cys: 0 9 0 9 0 0 0 0 0 0 0 9 0 0 9 % C
% Asp: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 9 0 0 17 0 0 0 9 0 0 0 0 0 % E
% Phe: 0 0 9 0 17 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 9 0 9 17 0 25 9 0 9 9 0 34 0 0 % G
% His: 0 0 9 0 0 0 0 0 17 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 9 0 0 0 0 9 0 0 0 0 % I
% Lys: 0 0 9 0 0 0 0 9 9 9 0 0 0 25 34 % K
% Leu: 9 9 9 0 9 25 9 0 9 0 9 0 9 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 9 0 17 0 0 0 17 9 0 0 9 0 0 0 % N
% Pro: 0 34 17 9 9 0 17 0 9 25 0 0 0 0 9 % P
% Gln: 9 0 0 0 0 0 0 9 9 9 0 0 9 0 0 % Q
% Arg: 9 9 9 17 0 0 17 0 0 0 0 9 9 17 9 % R
% Ser: 25 17 0 9 17 25 0 42 25 34 17 17 42 34 17 % S
% Thr: 9 0 0 9 17 9 0 9 0 0 34 9 0 0 0 % T
% Val: 9 0 25 9 9 0 9 9 17 9 17 9 0 0 9 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _